How can you handle a spouse that is continuously con condescending towards you?

There is no way I wouldn't ever split up the family, but putting up with her condescending remarks is hard to do. I have talked to here about on many occasions, to no avail.i feel a wedge between us as I just don't feel attracted anymore, but leaving is not an option. There has to be a way to get more respect, she has a collage degree and I do not.